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Cialis is a treatment for erectile dysfunction. You can buy Cialis online on the websites of pharmacies or specialized online stores.

The main active ingredient

Cialis is available as an oral tablet. The drug contains the active ingredient tadalafilum at a dosage of 5 mg.

Operating principle

All modern drugs to improve potency, including Cialis (tadalafilum), contain active substances, the mechanism of action of which is based on suppressing the activity (inhibition) of the phosphodiesterase type 5 enzyme (PDE-5).

In addition to type 5 PDE, the human body contains more than 10 forms of this enzyme, which are located in the myocardium, retina, lungs, skeletal muscles, brain, and vascular wall.

An erection develops due to increased blood flow to the corpora cavernosa of the penis. Small arteries and arterioles dilate, providing increased blood flow, under the influence of two factors: nitric oxide, produced by stimulation of the genitals, and cyclic guanosine monophosphate (cGMP). The level of cGMP in the corpora cavernosa depends on two factors, namely the amount of its synthesis and the rate of breakdown. It is the cleavage of cGMP in the cavernous bodies that occurs under the influence of PDE-5. Thus tadalafilum by inhibiting PDE-5, lead to an increase in cGMP levels and contribute to the development of an erection of proper strength.

One of the important nuances is that these drugs do not cause sexual arousal, which is a complex neuropsychic, behavioral, hormonal and physiological process; they do not lead to the development of an erection without external stimulation of the penis.

Indications

Indications for use of Cialis:

Treatment of erectile dysfunction of any severity caused by diseases of the pelvic organs, urinary or reproductive system, incl. past injuries, surgery, birth defects;
Treatment of erectile dysfunction of any severity associated with psychological problems and complexes in relation to intimacy, genitals, own body, etc.

Contraindications

Among the absolute contraindications for taking Cialis are:

Individual intolerance to the drug, allergic reactions in response to its intake;
Taking nitrates and nitric oxide donors, alpha-blockers, calcium channel blockers, angiotensin receptor blockers, and other vasodilating drugs. When these drugs are combined with a PDE-5 inhibitor, there is a risk of systemic vasodilation and a sharp drop in blood pressure.

Relative contraindications include:

Taking erythromycinum, ketoconazolum, indinavirum and ritonavirum. These drugs pass in the liver through the same enzyme systems as tadalafilum;
Deformity of the penis, congenital, acquired character. There is a risk of developing uncontrolled painful erection while taking PDE-5 inhibitors;
Increased risk of bleeding;
Tendency to priapism (uncontrolled long-lasting erection);
Diseases of the cardiovascular system: arterial hypertension, hypotension, angina pectoris, heart failure, heart rhythm disturbances;
Severe renal dysfunction;
Severe liver dysfunction.

Side effects

The nature of the side effects is the same for all three drugs, but the frequency of their occurrence is different. Taking Cialis causes adverse reactions in only 11% of patients, including:

Pain in the head. Presumably, they are associated with vasodilation in the membranes of the brain, or with an increase in blood pressure against the background of physical exertion with intimacy;
Digestive upset. It manifests itself in the form of heartburn, diarrhea, nausea, pain in the abdomen;
Redness of the face, a feeling of hot flashes. Associated with vasodilation and increased blood flow;
Nasal congestion. It is caused by swelling of the mucous membrane due to the expansion of its vessels;
Pain in muscles, back.

Instructions for use

The tablet should be taken orally, without chewing or dividing, and washed down with a moderate amount of water 2 to 3 hours before the expected sexual intercourse. The drug begins to act after 60 – 90 minutes, and its effect lasts up to 5-6 hours.

Analogues and substitutes

Cialis is a brand-name drug that sells for substantial money. You can buy generic Cialis for a lower amount under the name “Dinamico Long”, “Tadalafil”, etc.

Viagra

Viagra is a cheaper replacement for Cialis. It contains the active ingredient sildenafilum and may cause more side effects. Among the benefits of Viagra are fast-acting tablets that dissolve in the mouth.

Levitra

Levitra is another analogue of Cialis that contains vardenafilum. The drug is more easily tolerated than Viagra, but in terms of its safety it is still inferior to tablets with tadalafilum. Levitra can also be found in the form of an orally soluble tablet.

Generic Viagra (drugs with sildenafilum)

If you want to save as much as possible on pills for potency, then you should pay attention to the generics of Viagra, which are produced in India. They may differ from the real Cialis not only in their low cost, but also in their lower efficiency. Sildenafil preparations:

Delgra;
Sildigra;
Suhagra;
Sildenafil.

Can I buy without a prescription

Officially, Cialis can only be dispensed with a doctor’s prescription. But if you started to be interested in the question “Where can I buy cheap Cialis online”, then in various online stores you can buy the drug without any difficulties. Buying a cheap Cialis online allows you to save money, time and effort in finding it, and the seller avoids unnecessary waste on staff, rental of premises and bureaucratic costs.